Active, methylated vitamins your body can actually use — built for the 40–60% with an MTHFR variant, and more absorbable for everyone else. Made in the USA, third-party tested.
METHL makes methylated multivitamins and active B vitamins your body can actually use — folate as 5-MTHF, B12 as methylcobalamin, never synthetic folic acid. Formulated for the 40–60% with an MTHFR variant, and more absorbable for everyone else. Shop the full methylated vitamin line below.
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One question — we’ll match you to the right formula.
Your everyday baseline — 19 active vitamins & minerals plus fermented organic greens, in one daily capsule. Built for MTHFR, absorbable for everyone.
Fast-absorbing, methylated B-complex with methylcobalamin & TMG in a clean glycerin base — for steady energy, mood and MTHFR support. Just drops a day.
The complete system — the daily multivitamin and the liquid B-complex together for full-spectrum methylation coverage, at the best price.
| What matters | Generic multi | METHL |
|---|---|---|
| Methylated, active B vitamins | ✕ | ✓ |
| Works with an MTHFR variant | ✕ | ✓ |
| Synthetic folic acid | Yes | Never |
| Fermented organic greens | ✕ | ✓ |
| Fillers & binders | Common | None |
| Glass bottle | ✕ | ✓ |
| Third-party tested | Rarely | ✓ |
“Formulated with bioavailable, methylated nutrients that support real absorption — especially important for those with MTHFR gene variants. A smart daily foundation for energy, immunity, and long-term wellness.”
“Absolutely the best vitamins I have ever taken. These vitamins are absolutely the best.”
“My wife and I really liked this multivitamin. We feel a difference and it doesn’t upset your stomach. We will order again.”
“Well tolerated, and I can finally feel a methylated vitamin actually working.”
“I optimized everything and still felt off. Twenty years chasing performance — triathlete, marathon runner, martial artist — and I still couldn’t feel the difference. A genetic test explained why: an MTHFR variant meant my body couldn’t use standard vitamins. So I built the one that didn’t exist on the shelf.”
We’re confident you’ll feel the difference. If you’re not completely satisfied, return it within 60 days for a full refund. No questions asked.
Take METHL daily to experience the difference.
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Return it and we’ll process your refund promptly.
5-MTHF folate, methylcobalamin, P5P — the coenzyme forms your body uses directly, no conversion required.
40–60% of people can’t convert synthetic folic acid. METHL skips the step — bioavailable for everyone.
Made in the USA, third-party tested, vegan, no fillers. Real ingredients, real results.
Methylated vitamins are nutrients delivered in their active, body-ready form — the version your cells use directly, with no conversion step. A conventional multivitamin leans on synthetic precursors like folic acid and cyanocobalamin that your body has to convert first. METHL skips that step: folate as 5-MTHF (L-methylfolate), B12 as methylcobalamin, and B6 as P5P.
Why it matters. An estimated 40–60% of people carry an MTHFR gene variant that limits how well they turn synthetic folic acid into usable folate. For them, an ordinary multivitamin can leave nutrients on the table. Methylated forms are bioavailable whether or not you carry the variant — a smart default for everyone, not only MTHFR.
Methylfolate vs folic acid. Folic acid is a cheap, synthetic compound; 5-MTHF is the active folate your body actually runs on. Choosing methylated folate means no conversion bottleneck and no unmetabolized folic acid left over. Read the full breakdown in our guide to methylfolate vs folic acid.
Which METHL is right for you? Start with the Methylated Multivitamin for a daily foundation — 19 active vitamins and minerals plus fermented organic greens. Add the Liquid B-Complex Drops (methylcobalamin + TMG) if energy, mood and B-vitamin support are your focus. The Bundle pairs both for full-spectrum coverage at the best value. Not sure which to pick? Our buyer’s guide to the best methylated multivitamin walks through what to look for. Every formula is made in the USA, third-party tested, vegan and non-GMO, with no synthetic fillers — backed by a 60-day money-back guarantee.
Most multivitamins are built on synthetic precursors your body has to convert before it can use them. If that conversion runs slow, you can take a vitamin every day and still run low. Here’s what that feels like, and what METHL does about it.
B vitamins turn food into usable energy. When they arrive as inactive forms your cells can’t use, the tank never really fills.
METHL uses methylcobalamin B12 and active B vitamins your cells use on contact, no conversion step in between.
Methylation helps build the neurotransmitters behind focus and mood. Weak conversion of folate and B12 can leave that process short.
METHL delivers 5-MTHF folate and methylcobalamin, the forms that feed methylation directly.
Roughly a third to half of people carry an MTHFR variant that slows the switch from folic acid to usable folate, so standard multis underdeliver.
METHL is built for MTHFR: it skips the conversion entirely with pre-activated folate. See the MTHFR guide.
Unconverted folic acid can build up in the blood. It’s cheap to manufacture, which is why most multivitamins still use it.
METHL uses no synthetic folic acid, only natural 5-MTHF. See the difference.
Cheap binders, fillers and hard tablets can limit how much actually reaches your bloodstream.
METHL is a clean vegan formula with no synthetic fillers, plus a fast-absorbing liquid B-Complex option.
Supplement quality varies widely, and most brands never show third-party proof.
Every METHL batch is third-party tested for purity and potency, vegan, non-GMO, made in the USA.
Your body uses methylation to build serotonin, dopamine and other mood chemicals. Weak B-vitamin status can leave that supply short.
METHL delivers 5-MTHF, methylcobalamin and P5P (B6), the active forms behind neurotransmitter production.
Folate, B12 and B6 work together to keep homocysteine in a healthy range. In inactive forms, they can’t do that job as well.
METHL provides all three as active, methylated forms your body can put to work directly.
Daily nutrient gaps can leave your defenses under-supported, especially through busy or high-stress stretches.
The Methylated Multivitamin adds an immunity blend: vitamin C from organic cherry and amla, plus zinc and selenium.
Vegan and vegetarian diets are often low in B12 and a few other nutrients that are hard to get from plants alone.
METHL is fully vegan and plant-derived, with B12 as methylcobalamin in a form your body absorbs.
Juggling five or six bottles is easy to start and hard to keep up. Most days something gets skipped.
METHL pulls your daily foundation, greens and immunity into one clean capsule, with the Bundle if you want B-Complex too.
Hard tablets, fillers and binders can sit heavily, so you stop taking them.
METHL skips synthetic fillers, and the fast-absorbing Liquid B-Complex is an easy no-pill option.
Methylated vitamins are already in their active, body-ready form. Standard multis use synthetic precursors like folic acid that your body must convert. METHL skips that step, delivering nutrients your cells can use immediately.
If you want a single daily foundation, start with the Methylated Multivitamin. If you’re focused on energy, mood and B-vitamins, choose the Liquid B-Complex Drops. Want full coverage at the best value? The Bundle pairs both. Use “Find your METHL” above to match in one tap.
Yes. Methylated forms are bioavailable for everyone, whether or not you carry the variant. You get the active nutrients either way, with no downside.
Most people notice steadier energy and mood within about 30 days of daily use, as consistent levels of the active nutrients build up.
Yes. Every batch is independently tested for purity and potency. METHL is organic, plant-derived, vegan and non-GMO, with no fillers or binders, in a glass bottle.
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Folic acid is a cheap synthetic form your body has to convert before it can use it. Methylfolate (5-MTHF) is the active folate your cells use directly. If you carry an MTHFR variant that conversion is limited — so methylfolate means no bottleneck and no unmetabolized folic acid left over.
Methylated B vitamins are well tolerated by most people. Because the active forms are potent, some people new to them notice a short adjustment period; taking them in the morning with food helps. If you have a specific health condition, check with your provider first.
METHL uses fully active forms across the board — 5-MTHF folate, methylcobalamin B12 and P5P B6 — with fermented organic greens, no synthetic folic acid and no fillers, in a glass bottle, made in the USA and third-party tested. The quick test for any brand: read the label. If you see folic acid or cyanocobalamin, it isn’t fully methylated.
Take your daily serving once a day, ideally with a meal so the fat-soluble nutrients absorb well. Follow the serving size printed on your bottle.
Shake well, then take 2 full droppers (2 mL) daily. You can take it straight, hold it under your tongue for a few seconds, or add it to water or juice.
Yes. They’re designed to work together, which is exactly what the Bundle is. The multivitamin covers your daily foundation while the liquid adds concentrated, fast-absorbing active B vitamins.
The Methylated Multivitamin is a complete daily foundation with vitamins, minerals, fermented organic greens and an immunity blend in a vegan capsule. The Liquid B-Complex is a focused dose of active B vitamins in a fast-absorbing liquid for energy, mood and methylation support.
Take the multivitamin capsule with food for the best absorption and the easiest-on-the-stomach experience. The Liquid B-Complex works with or without food.
Morning is ideal. B vitamins support energy production, so most people prefer them earlier in the day rather than right before bed.
About a month. Each 2 fl oz bottle holds roughly 30 daily servings at the 2 mL dose.
Stick to the label. With B vitamins, more is not better, and there’s no benefit to doubling up. If you have questions about dosing for your situation, ask your healthcare provider.
Just take your next dose as usual. Methylated vitamins work best with steady daily use, so consistency matters more than any single day.
Yes. METHL is built for daily use. You don’t need to cycle off it.
5-MTHF (L-methylfolate), the active, body-ready form of folate, never synthetic folic acid. Read the full 5-MTHF guide.
Methylcobalamin, the active form of B12, rather than cheaper synthetic cyanocobalamin.
P5P (pyridoxal-5-phosphate), the active coenzyme form of vitamin B6 your body can use directly.
No. METHL never uses synthetic folic acid. You get natural 5-MTHF instead, which is especially important if you have an MTHFR variant. Here’s why that matters.
Yes. It includes a fermented organic greens blend alongside the methylated vitamins, minerals and an immunity blend with vitamin C from organic cherry and amla berry, plus zinc and selenium.
Anyone who wants reliably absorbable nutrients. Active forms benefit everyone, and they’re particularly useful if you have an MTHFR variant, eat a limited diet, or feel low on energy despite taking a standard multi.
Yes. METHL is formulated for adults of any gender who want active, methylated nutrition.
Yes. Both the Methylated Multivitamin and the Liquid B-Complex are vegan and plant-derived, including the capsule.
Yes. METHL is gluten-free and non-GMO, with no synthetic fillers.
Yes. The Liquid B-Complex is soy-free, sugar-free, alcohol-free and oil-free, with no synthetic preservatives.
No. METHL is fully plant-derived and vegan, so there are no dairy or animal ingredients.
No added sugar. It’s naturally sweet on its own, with no sugar, alcohol or synthetic sweeteners.
The pleasant taste comes from the plant-derived, self-preserving formula itself, not from added sugar or artificial sweeteners.
METHL is made in the USA and every batch is third-party tested for purity and potency.
Keep them in a cool, dry place away from direct light and heat. Always reseal the cap, and follow any storage note on your label.
Yes. Shake well before each use so the active nutrients are evenly distributed in every dropper.
It can, and that’s harmless. The bright color comes from riboflavin (B2) and simply means your body is passing what it doesn’t need that day.
Usually yes, but always check with your healthcare provider first if you take prescription medication or other supplements, so they can confirm it fits your routine.
Talk to your OB or healthcare provider before starting any supplement during pregnancy or breastfeeding. Many clinicians favor the active 5-MTHF form of folate, but your provider should guide what’s right for you.
Most multivitamins rely on synthetic precursors like folic acid and cyanocobalamin that your body must convert. METHL delivers the active forms directly, in a clean vegan formula with greens and an immunity blend, third-party tested and made in the USA.
Plus the occasional note on methylation, MTHFR and feeling like yourself again.
